Synchronous intramolecular cycloadditions of the polyene macrolactam polyketide heronamide C.
نویسندگان
چکیده
A growing number of natural products appear to arise from biosynthetic pathways that involve pericyclic reactions. We show here that for the heronamides this can occur via two spontaneous pathways involving alternative thermal or photochemical intramolecular cycloadditions.
منابع مشابه
Draft Genome Sequence of Streptomyces sp. TP-A0871, a Producer of Heronamide C
Streptomyces sp. TP-A0871 produces the polyene macrolactam heronamide C. Here, we report its draft genome sequence to get insight into heronamide biosynthesis and genome-mining for novel secondary metabolites of polyketide and nonribosomal peptide classes. The genome encodes over nine orphan gene clusters for polyketide and/or nonribosomal peptide syntheses.
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ورودعنوان ژورنال:
- Chemical communications
دوره 52 38 شماره
صفحات -
تاریخ انتشار 2016